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Home ProductsActive Pharmaceutical Ingredient98% Min Assay Active Pharmaceutical Ingredient Suramin Sodium API Powder CAS 129-46-4

98% Min Assay Active Pharmaceutical Ingredient Suramin Sodium API Powder CAS 129-46-4

98% Min Assay Active Pharmaceutical Ingredient Suramin Sodium API Powder CAS 129-46-4

Product Details:

Place of Origin: China
Brand Name: ORI
Certification: KOSHER/ISO9001/SGS
Model Number: XALY

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Packaging Details: Double food grade plastics inside; Environmental protection carton/barrel outside or Customized packages.
Delivery Time: 3-5 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: Negotiation
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Detailed Product Description
Other Name: Suramin Hexasodium Salt; Suramin Hexasodium; Suramin Sodium Salt Formula: C51H34N6O23S6•6Na
Formula Weight: 1429.17 G·mol−1 CAS: 129-46-4
Color: White To Light Yellow Powder Assay: 99%

High purity Suramin Sodium 98% min API powder CAS No 129-46-4

 

 

Product Name

Suramin Sodium
CAS No. 129-46-4
EINECS 207-280-5
Molecular Formula C51H34N6O23S6•6Na
Molecular Weight 1429.17 g·mol−1
Chemical Names

Suramin hexasodium salt; Suramin hexasodium;

Suramin sodium salt

Purity ≥98%
Usage

A G protein uncoupler and inhibitor of PDGF,

EGF, TGFb, SIRT1 and SIRT5

Character White to light yellow powder
Solubility Water very soluble
Standard USP EP JP etc.
Delivery method EMS, DHL, TNT, FedEx
 
Description:

Suramin Sodium is actually a sodium salt type of suramin, a polysulphonated naphthylurea with prospective antineoplastic activity. Suramin blocks the binding of several development components, like insulin-like improvement element I (IGF-I), epidermal improvement element (EGF), platelet-derived improvement aspect (PDGF), and tumor improvement factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial improvement situation (VEGF)- and basic fibroblast development element (bFGF)-induced angiogenesis; retroviral reverse transcriptase; uncoupling of G-proteins from receptors; topoisomerases; cellular folate transport; and steroidogenesis.

Soluble in water (50 mg/mL), 95% ethanol, and DMSO (ten mM). Insoluble in benzene, ether, and chloroform.

 

High purity Suramin Sodium 98% min API powder CAS No 129-46-4

 

 



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